Objective: Little is known about the impact of orlistat on the leptin system.We studied the plasma leptin and satiety sensation response for two days of orlistat treatment without hypocaloric diet and weight loss.Material and methods: Twenty obese female subjects were recruited from our medical outpatient clinics.All of these subjects had previousl
IntroductionThis study examined associations between screen time and addictive use (i.e., heavy involvement and negative consequences) of gaming and social media, and their independent effects on health outcomes.MethodsSurvey data were collected from 2,265 participants (mean age = 21.57).Internet Gaming Disorder (IGD) and Social Media Disorder (SMD
Damage and disease of nerves activates the complement system.We demonstrated that activation of the terminal pathway of the complement system leads to the royal nomadic 5413 rug formation of the membrane attack complex (MAC) and delays regeneration in the peripheral nervous system.Animals deficient in the complement component C6 showed improved rec
Background/Aims: Monitoring the appearance and progression of tumors are important for improving the survival rate of patients with ovarian cancer.This study aims to examine circulating tumor cells (CTCs) in epithelial ovarian cancer (EOC) patients to evaluate their clinical significance in comparison to the existing biomarker CA125.Methods: Immuom
Cost-sensitive learning is a popular paradigm to address class-imbalance learning (CIL) problem.Traditional cost-sensitive learning approaches always solve CIL problem by assigning a constant higher training error penalty for all minority instances than that of majority instances, but ignore the significance of location information.Therefore, sever